In My Hero Academia's chapter 417, Deku has transferred all of the One for All vestiges to Shigaraki, leaving him quirkless in the final fight. This mirrors his journey as a hero, starting as a quirkless child inspired by heroism. Just like when he saved Bakugo without powers, Deku must now save Shigaraki. With the true vestige Yoichi now in Shigaraki, the final battle will test Deku's heroism. This reflects the series' theme of becoming the greatest hero, starting with Deku's quirkless beginnings.
As the end nears, Deku's quirkless state in the final fight will show his growth and legacy as the greatest hero. The series' full circle from quirkless hero to legendary savior highlights Deku's journey and heroic spirit.