Handling a large defensive snake can be challenging, but there are ways to avoid getting bitten and safely wrap the snake. First, stay calm and move slowly to prevent startling the snake further. Keep a safe distance and avoid sudden movements. Use a tool like a snake hook to gently manipulate the snake and guide it away from you. If you need to pick up the snake, do so carefully and securely behind the head to prevent it from striking. Remember to keep your hands and fingers away from the snake's mouth to avoid getting bitten.

Finally, if necessary, you can use a snake bag or pillowcase to safely contain the snake for transportation. By following these steps, you can handle a large defensive snake without getting bitten and ensure the safety of both yourself and the snake.